Origin and Habitat: Cuatrocienagas, Coahuila, Mexico

• Mammillaria spinosissima var. mirabilis (Ehrenb.) Gürke
• Cactus mirabilis Kuntze
• Mammillaria mirabilis Ehrenb.
• Mammillaria seegeri var. mirabilis (Ehrenb.) Labour.

• Mammillaria spinosissima Lem.
• Cactus spinosissimus (Lem.) Kuntze
• Neomammillaria spinosissima (Lem.) Britton & Rose
• Mammillaria centraliplumosa Fittkau
• Mammillaria centraliplumosa var. gracilis Repp.
• Mammillaria gasterantha Repp.
• Mammillaria haasii J.Meyran
• Mammillaria hermannii var. flavicans Salm-Dyck
• Mammillaria pitcayensis Bravo
• Mammillaria pretiosa var. cristata Hildm. ex C.F.Först.
• Mammillaria spinosissima var. auricoma f. cristata hort.
• Mammillaria spinosissima var. aurorea (Ehrenb.) Gürke
• Cactus auroreus Kuntze
• Mammillaria aurorea Ehrenb.
• Mammillaria spinosissima brunnea Salm-Dyck
• Mammillaria spinosissima f. brunnea (Salm-Dyck) Gürke
• Mammillaria spinosissima var. castaneoides (Lem.) Borg in Borg
• Mammillaria castaneoides Lem.
• Mammillaria spinosissima f. cristata
• Mammillaria spinosissima var. eximia (Ehrenb.) Gürke
• Cactus eximius (Ehrenb.) Kuntze
• Mammillaria eximia Ehrenb.
• Mammillaria spinosissima f. eximia (Ehrenb.) Schelle
• Mammillaria spinosissima var. flavida Salm-Dyck
• Mammillaria spinosissima f. flavida (Salm-Dyck) Gürke
• Mammillaria spinosissima var. genuina Gürke
• Mammillaria spinosissima var. haseloffii (Ehrenb.) Gürke
• Mammillaria haseloffii Ehrenb.
• Mammillaria spinosissima var. hepatica (Ehrenb.) Labour.
• Mammillaria hepatica Ehrenb.
• Mammillaria seegeri var. gracilispina Salm-Dyck
• Mammillaria spinosissima var. herrmannii (Ehrenb.) Gürke
• Mammillaria herrmannii Ehrenb.
• Mammillaria spinosissima var. isabellina (Ehrenb.) Gürke
• Cactus isabellinus (Ehrenb.) Kuntze
• Mammillaria isabellina Ehrenb.
• Mammillaria spinosissima f. isabellina (Ehrenb.) Schelle
• Mammillaria spinosissima var. linkeana (Ehrenb.) Gürke
• Cactus linkeanus Kuntze
• Mammillaria linkeana Ehrenb.
• Mammillaria spinosissima var. mirabilis (Ehrenb.) Gürke
• Cactus mirabilis Kuntze
• Mammillaria mirabilis Ehrenb.
• Mammillaria seegeri var. mirabilis (Ehrenb.) Labour.
• Mammillaria spinosissima f. monstruosa hort.
• Mammillaria spinosissima var. polyacantha (Ehrenb.)
• Mammillaria polyacantha Ehrenb.
• Mammillaria spinosissima var. pretiosa (Ehrenb.) Scheele
• Cactus pretiosus (Ehrenb.) Kuntze
• Mammillaria pretiosa Ehrenb.
• Mammillaria spinosissima var. pruinosa (Ehrenb.) Gürke
• Mammillaria pruinosa Ehrenb.
• Mammillaria seegeri var. pruinosa (Ehrenb.) Salm-Dyck
• Mammillaria spinosissima var. pulcherrima (Ehrenb.) Gürke
• Cactus pulcherrimus (Ehrenb.) Kuntze
• Mammillaria pulcherrima Ehrenb.
• Mammillaria spinosissima f. rubens (Salm-Dyck) Gürke
• Mammillaria spinosissima rubens Salm-Dyck
• Mammillaria spinosissima f. rubrispina cristata hort.
• Mammillaria spinosissima f. rubrispina hort.
• Mammillaria spinosissima var. sanguinea (F.Haage) F.Haage in L.H.Bailey ex Brandegee
• Mammillaria sanguinea F.Haage ex Regel
• Mammillaria spinosissima var. seegeri (Ehrenb.) Gürke
• Mammillaria seegerii Ehrenb.
• Mammillaria spinosissima f. tepoztlanensis Bravo
• Mammillaria spinosissima f. typica Gürke
• Mammillaria spinosissima var. vulpina (Ehrenb.) Gürke
• Cactus vulpinus var. Kuntze (Ehrenb.) Kuntze
• Mammillaria vulpina var. Ehrenb. Ehrenb.
• Mammillaria virginis Fittkau & Kladiwa in Krainz

• Mammillaria spinosissima subs. pilcayensis (Bravo) D.R.Hunt
• Mammillaria pilcayensis Bravo
• Mammillaria pilcayensis var. chrysodactyla Appenz.
• Mammillaria chrysodactyla Appenz.

• Mammillaria spinosissima subs. tepoxtlana D.R.Hunt
• Mammillaria crassior Repp.
• Mammillaria spinosissima var. auricoma (A.Dietr.) Gürke
• Cactus auricomus (A.Dietr.) Kuntze
• Mammillaria auricoma A.Dietr.
• Mammillaria spinosissima f. auricoma (A.Dietr.) Schelle

• Mammillaria spinosissima cv. Un Pico
• Mammillaria spinosissima cv. Un Pico cristata
• Mammillaria spinosissima cv. Un Pico Monstruosa

Description: Mammillaria lasiacanthaSN|9075]]SN|9075]] are usually unbranched or slowly clustering, deep-seated in substrate and inconspicuous.
Stems: Depressed-spheric to short cylindric, 1-3.5cm wide × 1,5-7 cm tall. axils bare.
Roots: Diffuse not enlarged.
Spines: 40-80 per areole, in several series but all equally thin, mostly appressed, white or very pale pink, often minutely tipped pinkish brown, innocuous, bristlelike, 0,5-6 mm, glabrous to plumose, all interpreted as radial, innermost spines shortest; No central spines.
Flowers: 1-2,5 cm; white or cream, usually with sharply defined midstripes of green, yellow, tan, pink, pale purple, or reddish, blooming from January to March
Fruits: Scarlet, cylindric or clavate, 10-25 mm long with floral remnant persistent ripening in June August.
"SB500": Adults of Mammillaria lasiacanthaSN|9075]]SN|9075]] usually have glabrous spines, but in the SB500 population all plants may retain plumose spines at maturity.

Cultivation and Propagation: This plant has not the fame to be easy to cultivate, but in good conditions with excellent ventilation, it grows without difficulty. It is especially sensitive to overwatering. So careful watering and an open mineral potting soil are a must. Avoid the use of peat or other humus sources in the potting mixture. Don't add limestone to the potting mix which must be moderately acidic. Can be sensitive to frost (but if dry they are resistant to -5° C). Requires maximum sun exposure to reach its full potential and to achieve success in flowering. A winter rest that allows the plant to shrivel (perhaps losing up to 25% of its summer height) will encourage flowering and long time survival. Be careful to encourage slow growth. Provide very good ventilation.

Propagation:: Direct sow after last frost. (it usually doesn't produces offsets).